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Johns Hopkins Coronavirus Resource Center
Testing Hub

Testing FAQ

These FAQs provide answers to some of the most frequently asked questions on COVID-19

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The Facts About COVID-19 Tests

COVID-19 tests are critical to measuring the spread of the disease and determining how to handle the pandemic. The two types of COVID-19 test – serology tests and viral tests – serve different purposes and have different limitations.

Knowing the facts about these tests is essential to making decisions that are best for the public’s health.

꧁❦༺aaaaa༻❦꧂Testing FAQ - Johns Hopkins Coronavirus Resource Center Created with Sketch.Download PDF
Serology

The Two Test Types

Question
Viral TestViral Test
Serology TestSerology Test
Question IconWhat is the test?
Viral Test:
A viral test is an oral or nasal swab or saliva test that looks for evidence of an active viral infection. There are two major types: a PCR test and an antigen test.
Serology Test:
A serology test is a blood test that looks for evidence of someone’s prior infection with the virus.
Check IconWhat does the test do?
Viral Test:
PCR tests look for the presence of a virus’s genetic material, while antigen tests look for specific proteins on a virus’s surface. Antigen tests produce results more quickly, but may be less sensitive.
Serology Test:
The test provides evidence that someone may have been exposed to the virus in the past, potentially even if they did not have symptoms, by detecting antibodies specific to the virus.
Cross IconWhat doesn't the test do?
Viral Test:
Viral tests do not indicate whether someone was infected in the past.
Serology Test:
The test does not diagnose an active infection or identify who is protected from reinfection (antibodies have not been proven to guarantee immunity).
FDA LogoHow does the FDA handle the test?
Viral Test:
The FDA formally evaluates these tests prior to use.
Serology Test:
The FDA does not formally evaluate these tests prior to use, though a few have Emergency Use Authorization.
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